Kimmel, H.L., O'Connor, J.A., Carroll, F.I., Howell, L.L. Faster onset and dopamine transporter selectivity predict stimulant and reinforcing effects of cocaine analogs in squirrel monkeys. Pharmacology Biochemistry and Behavior, 86: 45-54, 2007 PDF.

Howell, L.L., Carroll, F.I., Votaw, J.R., Goodman, M.M., Kimmel, H.L. Effects of combined dopamine and serotonin transporter inhibitors on cocaine self-administration in rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics, 320: 757-765, 2007 PDF.

Carroll, F.I., Howard, J.L., Howell, L.L., Fox, B.S., Kuhar, M.J. Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse. American Association of Pharmaceutical Scientists Journal, 8: E196-203, 2006 PDF.

Plisson, C., Jarkas, N., McConathy, J., Voll, R.J., Votaw, J., Williams, L., Howell, L.L., Kilts, C.D., Goodman, M.M. Evaluation of carbon-11-labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)phenyl]nortropane as a potential radioligand for imaging the serotonin transporter by PET. Journal of Medicinal Chemistry, 49: 942-6, 2006 PDF.

Howell, L.L., Wilcox, K.M., Lindsey, K.P., Kimmel, H.L. Olanzapine-induced suppression of cocaine self-administration in rhesus monkeys. Neuropsychopharmacology, 31: 585-593, 2006 PDF.

Fantegrossi, W.E., Harrington, A.W., Kiessel, C.L., Eckler, J.R., Rabin, R.A., Winter, J.C., Coop, A., Rice, K.C., Woods, J.H. Hallucinogen-like actions of 5-methoxy-N,N-diisopropyltryptamine in mice and rats. Pharmacology Biochemistry and Behavior, 83: 122-9, 2006 PDF.

Wilcox, K.M., Kimmel, H.L., Lindsey, K.P., Votaw, J.R., Goodman, M.M., Howell, L.L. In vivo comparison of the reinforcing and dopamine transporter effects of local anesthetics in rhesus monkeys. Synapse, 58: 220-228, 2005. PDF.

Carroll, F.I., Blough, B.E., Nie, Z., Kuhar, M.J., Howell, L.L., Navarro, H.A. Synthesis and monoamine transporter binding properties of 3beta-(3',4'-disubstituted phenyl)tropane-2beta-carboxylic acid methyl esters. Journal of Medicinal Chemistry, 48: 2767-2771, 2005. PDF.

Kimmel, H.L., Ginsburg, B.C., Howell, L.L. Changes in extracellular dopamine during cocaine self-administration in squirrel monkeys. Synapse, 56: 129-134, 2005. PDF.

Ginsburg, B.C., Kimmel, H.L., Carroll, F.I., Goodman, M.M., Howell, L.L. Interaction of cocaine and dopamine transporter inhibitors on behavior and neurochemistry in monkeys. Pharmacology Biochemistry and Behavior, 80: 481-491, 2005. PDF.

Lindsey, K.P., Wilcox, K.M., Votaw, J.R., Goodman, M.M., Plisson, C., Carroll, F.I., Rice, K.C., Howell, L.L. Effects of dopamine transporter inhibitors on cocaine self-administration in rhesus monkeys: relationship to transporter occupancy determined by positron emission tomography neuroimaging. Journal of Pharmacology and Experimental Therapeutics, 309: 959-969, 2004. PDF.

Wilcox, K.M., Lindsey, K.P., Votaw, J.R., Goodman, M.M., Martarello, L., Carroll, F.I. and Howell, L.L. Self-administration of cocaine and the cocaine analog RTI-113: Relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus monkeys. Synapse, 43: 78-85, 2002. PDF.

Czoty, P.W., Ginsburg, B.C. and Howell, L.L. Serotonergic attenuation of the reinforcing and neurochemical effects of cocaine in squirrel monkeys. Journal of Pharmacology and Experimental Therapeutics, 300: 831-7, 2002. PDF.

Howell, L.L., Hoffman, J. M., Votaw, J.R., Landrum, A.M., Wilcox, K.M. and Lindsey, K.P. Cocaine-induced brain activation determined by positron emission tomography (PET) neuroimaging in conscious rhesus monkeys. Psychopharmacology, 159: 154-160, 2002. PDF.

Votaw, J.R., Howell, L.L., Martarello, L., Hoffman, J.M., Kilts, C.D., Lindsey, K.P., Goodman, M.M. Measurement of dopamine transporter occupancy for multiple injections of cocaine using a single injection of [F-18]FECNT. Synapse, 44:203-210, 2002. PDF.

Howell, L.L., Wilcox, K.M. Functional imaging and neurochemical correlates of stimulant self-administration in primates. Psychopharmacology, 163:352-61, 2002. PDF.

Howell, L.L., Hoffman, J.M., Votaw, J.R., Landrum, A.M. and Jordan, J.F. An apparatus and behavioral training protocol to conduct positron emission tomography (PET) neuroimaging in conscious rhesus monkeys. Journal of Neuroscience Methods, 106: 161-169, 2001. PDF.

Howell, L.L., Schama, K.F., Ellis, J.E., Grimley, P.J., Kitchens, A.J. and Byrd, L.D. Fetal development in rhesus monkeys exposed prenatally to cocaine. Neurotoxicology and Teratology, 23: 133-140, 2001.

Howell, L.L. and Wilcox, K.M. The dopamine transporter and cocaine medication development: Drug self-administration in nonhuman primates. Journal of Pharmacology and Experimental Therapeutics, 298: 1-6, 2001. PDF.

Howell, L.L. and Wilcox, K.M. Intravenous drug self-administration in nonhuman primates. In: Methods of Behavior Analysis in Neuroscience, J.J. Buccafusco, Ed. CRC Press: Boca Raton, FL, pp. 91-110, 2001.

Howell, L.L., Czoty, P.W., Kuhar, M.J. and Carroll, F.I. Comparative behavioral pharmacology of cocaine and the selective dopamine uptake inhibitor, RTI-113, in the squirrel monkey. Journal of Pharmacology and Experimental Therapeutics, 292: 521-529, 2000. PDF.

Czoty, P.W., Justice, J.B, Jr. and Howell, L.L. Cocaine-induced changes in extracellular dopamine determined by microdialysis in awake squirrel monkeys. Psychopharmacology, 148: 299-306, 2000. PDF.

Czoty, P.W. and Howell, L.L. Behavioral effects of AMI-193, a 5-HT_2A- and dopamine D2-receptor antagonist, in the squirrel monkey. Pharmacology, Biochemistry and Behavior, 67: 257-264, 2000.

Howell, L.L., Byrd, L.D., McDonough, A.M., Iuvone, P.M. and Bakay, R.A.E. Behavioral evaluation of hemiparkinsonian MPTP monkeys following dopamine pharmacological manipulation and adrenal co-graft transplantation. Cell Transplantation, 9: 609-622, 2000.

Last updated 31 JUL 07